6f7a: Difference between revisions

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'''Unreleased structure'''


The entry 6f7a is ON HOLD
==Gloeobacter Ligand-gated Ion Channel (GLIC) closed state crystallized in an ultra-swollen lipidic mesophase==
 
<StructureSection load='6f7a' size='340' side='right' caption='[[6f7a]], [[Resolution|resolution]] 6.00&Aring;' scene=''>
Authors: Martiel, I., Zabara, A., Chong, J.Y.T., Stark, L., Cromer, B., Dummond, C.J., Mezzenga, R.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6f7a]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F7A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F7A FirstGlance]. <br>
Description: Gloeobacter Ligand-gated Ion Channel (GLIC) closed state crystallized in an ultra-swollen lipidic mesophase
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f7a OCA], [http://pdbe.org/6f7a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f7a RCSB], [http://www.ebi.ac.uk/pdbsum/6f7a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f7a ProSAT]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
[[Category: Chong, J.Y.T]]
== Function ==
[[Category: Dummond, C.J]]
[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> 
[[Category: Zabara, A]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Chong, J Y.T]]
[[Category: Cromer, B]]
[[Category: Dummond, C J]]
[[Category: Martiel, I]]
[[Category: Martiel, I]]
[[Category: Mezzenga, R]]
[[Category: Stark, L]]
[[Category: Stark, L]]
[[Category: Mezzenga, R]]
[[Category: Zabara, A]]
[[Category: Cromer, B]]
[[Category: Membrane protein]]
[[Category: Transport protein]]

Revision as of 09:37, 15 February 2018

Gloeobacter Ligand-gated Ion Channel (GLIC) closed state crystallized in an ultra-swollen lipidic mesophaseGloeobacter Ligand-gated Ion Channel (GLIC) closed state crystallized in an ultra-swollen lipidic mesophase

Structural highlights

6f7a is a 5 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.[1]

References

  1. ↑ Bocquet N, Prado de Carvalho L, Cartaud J, Neyton J, Le Poupon C, Taly A, Grutter T, Changeux JP, Corringer PJ. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature. 2007 Jan 4;445(7123):116-9. Epub 2006 Dec 10. PMID:17167423 doi:10.1038/nature05371

6f7a, resolution 6.00Å

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OCA
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