2i3y: Difference between revisions

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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i3/2i3y_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i3/2i3y_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Arrowsmith, C]]
[[Category: Arrowsmith, C]]
[[Category: Bunkoczi, G]]
[[Category: Bunkoczi, G]]
[[Category: Delft, F Von]]
[[Category: Delft, F von]]
[[Category: Edwards, A]]
[[Category: Edwards, A]]
[[Category: Gileadi, O]]
[[Category: Gileadi, O]]

Revision as of 09:38, 31 January 2018

Crystal structure of human glutathione peroxidase 5Crystal structure of human glutathione peroxidase 5

Structural highlights

2i3y is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:GPX5 (HUMAN)
Activity:Glutathione peroxidase, with EC number 1.11.1.9
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[GPX5_HUMAN] Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2i3y, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA