5lba: Difference between revisions
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<StructureSection load='5lba' size='340' side='right' caption='[[5lba]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='5lba' size='340' side='right' caption='[[5lba]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5lba]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LBA FirstGlance]. <br> | <table><tr><td colspan='2'>[[5lba]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LBA FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6SV:1-CYCLOHEXYL-3-[[(2~{R})-OXOLAN-2-YL]METHYL]UREA'>6SV</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6SV:1-CYCLOHEXYL-3-[[(2~{R})-OXOLAN-2-YL]METHYL]UREA'>6SV</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RECQL5, RECQ5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lba OCA], [http://pdbe.org/5lba PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lba RCSB], [http://www.ebi.ac.uk/pdbsum/5lba PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lba ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lba OCA], [http://pdbe.org/5lba PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lba RCSB], [http://www.ebi.ac.uk/pdbsum/5lba PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lba ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: DNA helicase]] | [[Category: DNA helicase]] | ||
[[Category: Human]] | |||
[[Category: Aitkenhead, H]] | [[Category: Aitkenhead, H]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
[[Category: Delft, F | [[Category: Delft, F von]] | ||
[[Category: Edwards, A M]] | [[Category: Edwards, A M]] | ||
[[Category: Gileadi, O]] | [[Category: Gileadi, O]] | ||
Revision as of 23:38, 24 January 2018
Crystal structure of human RECQL5 helicase in complex with DSPL fragment(1-cyclohexyl-3-(oxolan-2-ylmethyl)urea, SGC - Diamond XChem I04-1 fragment screening.Crystal structure of human RECQL5 helicase in complex with DSPL fragment(1-cyclohexyl-3-(oxolan-2-ylmethyl)urea, SGC - Diamond XChem I04-1 fragment screening.
Structural highlights
Function[RECQ5_HUMAN] May have an important role in DNA metabolism. |
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