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== | |||
==The crystal structure of the human RND1 GTPase in the active GTP bound state== | |||
<StructureSection load='2cls' size='340' side='right' caption='[[2cls]], [[Resolution|resolution]] 2.31Å' scene=''> | <StructureSection load='2cls' size='340' side='right' caption='[[2cls]], [[Resolution|resolution]] 2.31Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2cls]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CLS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CLS FirstGlance]. <br> | <table><tr><td colspan='2'>[[2cls]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CLS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CLS FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cls FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cls OCA], [http://pdbe.org/2cls PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cls RCSB], [http://www.ebi.ac.uk/pdbsum/2cls PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cls FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cls OCA], [http://pdbe.org/2cls PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cls RCSB], [http://www.ebi.ac.uk/pdbsum/2cls PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cls ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cl/2cls_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cl/2cls_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 16: | Line 17: | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cls ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cls ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
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[[Category: Colebrook, S]] | [[Category: Colebrook, S]] | ||
[[Category: Debreczeni, J E]] | [[Category: Debreczeni, J E]] | ||
[[Category: Delft, F | [[Category: Delft, F von]] | ||
[[Category: Doyle, D]] | [[Category: Doyle, D]] | ||
[[Category: Edwards, A]] | [[Category: Edwards, A]] | ||
Revision as of 21:47, 24 January 2018
The crystal structure of the human RND1 GTPase in the active GTP bound stateThe crystal structure of the human RND1 GTPase in the active GTP bound state
Structural highlights
Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Human
- Arrowsmith, C
- Bray, J
- Colebrook, S
- Debreczeni, J E
- Delft, F von
- Doyle, D
- Edwards, A
- Elkins, J
- Gileadi, O
- Hwa, L Wen
- Marsden, B
- Pike, A C.W
- Schoch, G
- Sobott, F
- Sundstrom, M
- Turnbull, A P
- Weigelt, J
- Yang, X
- Zhao, Y
- Cytoskeleton
- Gtp-binding
- Gtp-binding protein rho6
- Lipoprotein
- Membrane
- Nucleotide binding protein
- Nucleotide-binding
- Prenylation
- Small gtpase