Phospholipase A1: Difference between revisions
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<StructureSection load='5dqx' size='340' side='right' caption=' | <StructureSection load='5dqx' size='340' side='right' caption='Phospholiase A1 complex with octylglucoside, glycerol and Ca+2 ion (green) (PDB code [[5dqz]])' scene=''> | ||
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'''Phospholipase A1''' (PLA1) hydrolyzes phospholipids to produce 2-acyl-lysophospholipids and fatty acids<ref>PMID:25436551</ref>. PLA1 preferentially hydrolyzes phosphatidic acid and PLA1-phosphatidic acid regulates mitochondria dynamics<ref>PMID:24599962</ref>. | '''Phospholipase A1''' (PLA1) hydrolyzes phospholipids to produce 2-acyl-lysophospholipids and fatty acids<ref>PMID:25436551</ref>. PLA1 preferentially hydrolyzes phosphatidic acid and PLA1-phosphatidic acid regulates mitochondria dynamics<ref>PMID:24599962</ref>. | ||
== Relevance == | == Relevance == | ||
Phosphatidylserine-specific PLA1 expression in colorectal cancer is associated with tumor invasion and metastasis<ref>PMID:25750298</ref>. | |||