1isi: Difference between revisions
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==Crystal Structure Analysis of BST-1/CD157 complexed with ethenoNAD== | ==Crystal Structure Analysis of BST-1/CD157 complexed with ethenoNAD== | ||
<StructureSection load='1isi' size='340' side='right' caption='[[1isi]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='1isi' size='340' side='right' caption='[[1isi]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1isi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ISI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ISI FirstGlance]. <br> | <table><tr><td colspan='2'>[[1isi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ISI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ISI FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ENQ:[[(2R,3S,4R,5R)-3,4-DIHYDROXY-5-(9H-IMIDAZO[2,1-F]PURIN-6-IUM-3-YL)OXOLAN-2-YL]METHOXY-OXIDANIDYL-PHOSPHORYL]+[(2R,3S,4R,5R)-3,4-DIHYDROXY-5-OXIDANIDYL-OXOLAN-2-YL]METHYL+PHOSPHATE'>ENQ</scene>, <scene name='pdbligand= | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ENQ:[[(2R,3S,4R,5R)-3,4-DIHYDROXY-5-(9H-IMIDAZO[2,1-F]PURIN-6-IUM-3-YL)OXOLAN-2-YL]METHOXY-OXIDANIDYL-PHOSPHORYL]+[(2R,3S,4R,5R)-3,4-DIHYDROXY-5-OXIDANIDYL-OXOLAN-2-YL]METHYL+PHOSPHATE'>ENQ</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NCA:NICOTINAMIDE'>NCA</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1isf|1isf]], [[1isg|1isg]], [[1ish|1ish]], [[1isj|1isj]], [[1ism|1ism]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1isf|1isf]], [[1isg|1isg]], [[1ish|1ish]], [[1isj|1isj]], [[1ism|1ism]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1isi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1isi OCA], [http://pdbe.org/1isi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1isi RCSB], [http://www.ebi.ac.uk/pdbsum/1isi PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1isi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1isi OCA], [http://pdbe.org/1isi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1isi RCSB], [http://www.ebi.ac.uk/pdbsum/1isi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1isi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/is/1isi_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/is/1isi_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||