1j7j: Difference between revisions

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==Crystal Structure of the HPRT from Salmonella typhimurium==
==Crystal Structure of the HPRT from Salmonella typhimurium==
<StructureSection load='1j7j' size='340' side='right' caption='[[1j7j]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1j7j' size='340' side='right' caption='[[1j7j]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j7j OCA], [http://pdbe.org/1j7j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1j7j RCSB], [http://www.ebi.ac.uk/pdbsum/1j7j PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j7j OCA], [http://pdbe.org/1j7j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1j7j RCSB], [http://www.ebi.ac.uk/pdbsum/1j7j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1j7j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j7/1j7j_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j7/1j7j_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j7j ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j7j ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Revision as of 12:06, 17 January 2018

Crystal Structure of the HPRT from Salmonella typhimuriumCrystal Structure of the HPRT from Salmonella typhimurium

Structural highlights

1j7j is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Hypoxanthine phosphoribosyltransferase, with EC number 2.4.2.8
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[HPRT_SALTY] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1j7j, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA