6bgf: Difference between revisions
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<StructureSection load='6bgf' size='340' side='right' caption='[[6bgf]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='6bgf' size='340' side='right' caption='[[6bgf]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6bgf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BGF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BGF FirstGlance]. <br> | <table><tr><td colspan='2'>[[6bgf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BGF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BGF FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine_dioxygenase Cysteine dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.20 1.13.11.20] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine_dioxygenase Cysteine dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.20 1.13.11.20] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bgf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bgf OCA], [http://pdbe.org/6bgf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bgf RCSB], [http://www.ebi.ac.uk/pdbsum/6bgf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bgf ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bgf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bgf OCA], [http://pdbe.org/6bgf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bgf RCSB], [http://www.ebi.ac.uk/pdbsum/6bgf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bgf ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Cysteine dioxygenase]] | [[Category: Cysteine dioxygenase]] | ||
[[Category: Human]] | |||
[[Category: Li, J]] | [[Category: Li, J]] | ||
[[Category: Liu, A]] | [[Category: Liu, A]] | ||
Revision as of 11:25, 17 January 2018
Crystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenaseCrystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenase
Structural highlights
Function[CDO1_HUMAN] Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range. |
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