6evd: Difference between revisions

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<StructureSection load='6evd' size='340' side='right' caption='[[6evd]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
<StructureSection load='6evd' size='340' side='right' caption='[[6evd]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6evd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EVD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EVD FirstGlance]. <br>
<table><tr><td colspan='2'>[[6evd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspnc Aspnc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EVD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EVD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BYN:hydroxylated+prenyl-FMN'>BYN</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BYN:hydroxylated+prenyl-FMN'>BYN</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fdc1, An03g06590 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=425011 ASPNC])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenacrylate_decarboxylase Phenacrylate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.102 4.1.1.102] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenacrylate_decarboxylase Phenacrylate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.102 4.1.1.102] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6evd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6evd OCA], [http://pdbe.org/6evd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6evd RCSB], [http://www.ebi.ac.uk/pdbsum/6evd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6evd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6evd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6evd OCA], [http://pdbe.org/6evd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6evd RCSB], [http://www.ebi.ac.uk/pdbsum/6evd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6evd ProSAT]</span></td></tr>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aspnc]]
[[Category: Phenacrylate decarboxylase]]
[[Category: Phenacrylate decarboxylase]]
[[Category: Bailey, S S]]
[[Category: Bailey, S S]]

Revision as of 12:02, 27 December 2017

Structure of R173A A. niger Fdc1 with prFMN in the hydroxylated formStructure of R173A A. niger Fdc1 with prFMN in the hydroxylated form

Structural highlights

6evd is a 1 chain structure with sequence from Aspnc. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:fdc1, An03g06590 (ASPNC)
Activity:Phenacrylate decarboxylase, with EC number 4.1.1.102
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[FDC1_ASPNC] Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.[HAMAP-Rule:MF_03196][1]

References

  1. Payne KA, White MD, Fisher K, Khara B, Bailey SS, Parker D, Rattray NJ, Trivedi DK, Goodacre R, Beveridge R, Barran P, Rigby SE, Scrutton NS, Hay S, Leys D. New cofactor supports alpha,beta-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition. Nature. 2015 Jun 25;522(7557):497-501. doi: 10.1038/nature14560. Epub 2015 Jun, 17. PMID:26083754 doi:http://dx.doi.org/10.1038/nature14560

6evd, resolution 1.19Å

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