5ujx: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5ujx is ON HOLD  until Paper Publication
+==Crystal structure of DHFR in 20% Isopropanol==
+<StructureSection load='5ujx' size='340' side='right' caption='[[5ujx]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-Authors: Cuneo, M.J., Agarwal, P.K.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5ujx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UJX FirstGlance]. <br>
-Description: Crystal structure of DHFR in 20% Isopropanol
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5e8q|5e8q]]</td></tr>
-[[Category: Agarwal, P.K]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr>
-[[Category: Cuneo, M.J]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ujx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ujx OCA], [http://pdbe.org/5ujx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ujx RCSB], [http://www.ebi.ac.uk/pdbsum/5ujx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ujx ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/C3TR70_ECOLX C3TR70_ECOLX]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]
+__TOC__
+</StructureSection>
+[[Category: Dihydrofolate reductase]]
+[[Category: Agarwal, P K]]
+[[Category: Cuneo, M J]]
+[[Category: Dynamic]]
+[[Category: Oxidoreductase]]