5eu9: Difference between revisions

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<StructureSection load='5eu9' size='340' side='right' caption='[[5eu9]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='5eu9' size='340' side='right' caption='[[5eu9]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5eu9]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EU9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5eu9]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EU9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5TX:((3S,5S)-1,5-DIHYDROXY-3-METHYL-2-OXOPYRROLIDIN-3-YL)PHOSPHONIC+ACID'>5TX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5TX:((3S,5S)-1,5-DIHYDROXY-3-METHYL-2-OXOPYRROLIDIN-3-YL)PHOSPHONIC+ACID'>5TX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zcw|4zcw]], [[4za0|4za0]], [[1te6|1te6]], [[2akm|2akm]], [[2akz|2akz]], [[3ucc|3ucc]], [[3ucd|3ucd]], [[3uje|3uje]], [[3ujf|3ujf]], [[3ujr|3ujr]], [[3ujs|3ujs]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zcw|4zcw]], [[4za0|4za0]], [[1te6|1te6]], [[2akm|2akm]], [[2akz|2akz]], [[3ucc|3ucc]], [[3ucd|3ucd]], [[3uje|3uje]], [[3ujf|3ujf]], [[3ujr|3ujr]], [[3ujs|3ujs]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ENO2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eu9 OCA], [http://pdbe.org/5eu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eu9 RCSB], [http://www.ebi.ac.uk/pdbsum/5eu9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eu9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eu9 OCA], [http://pdbe.org/5eu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eu9 RCSB], [http://www.ebi.ac.uk/pdbsum/5eu9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eu9 ProSAT]</span></td></tr>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Phosphopyruvate hydratase]]
[[Category: Phosphopyruvate hydratase]]
[[Category: Leonard, P G]]
[[Category: Leonard, P G]]

Revision as of 12:55, 22 November 2017

Structure of Human Enolase 2 in complex with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acidStructure of Human Enolase 2 in complex with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid

Structural highlights

5eu9 is a 8 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:ENO2 (HUMAN)
Activity:Phosphopyruvate hydratase, with EC number 4.2.1.11
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[ENOG_HUMAN] Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).

5eu9, resolution 2.05Å

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