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<StructureSection load='5uqh' size='340' side='right' caption='[[5uqh]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='5uqh' size='340' side='right' caption='[[5uqh]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5uqh]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UQH FirstGlance]. <br> | <table><tr><td colspan='2'>[[5uqh]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni_jejuni Campylobacter jejuni jejuni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UQH FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8L1:N-{4-CHLORO-3-[4-(TRIFLUOROMETHYL)-1,3-THIAZOL-2-YL]PHENYL}-N-(2-{3-[(1E)-N-HYDROXYETHANIMIDOYL]PHENYL}PROPAN-2-YL)UREA'>8L1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8L1:N-{4-CHLORO-3-[4-(TRIFLUOROMETHYL)-1,3-THIAZOL-2-YL]PHENYL}-N-(2-{3-[(1E)-N-HYDROXYETHANIMIDOYL]PHENYL}PROPAN-2-YL)UREA'>8L1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r7j|4r7j]], [[4mz1|4mz1]], [[4mz8|4mz8]], [[5uqf|5uqf]], [[5uqg|5uqg]], [[5upu|5upu]], [[5upv|5upv]], [[5upx|5upx]], [[5upy|5upy]], [[5urq|5urq]], [[5urr|5urr]], [[5urs|5urs]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r7j|4r7j]], [[4mz1|4mz1]], [[4mz8|4mz8]], [[5uqf|5uqf]], [[5uqg|5uqg]], [[5upu|5upu]], [[5upv|5upv]], [[5upx|5upx]], [[5upy|5upy]], [[5urq|5urq]], [[5urr|5urr]], [[5urs|5urs]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaB, Cj8486_1016 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32022 Campylobacter jejuni jejuni])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uqh OCA], [http://pdbe.org/5uqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uqh RCSB], [http://www.ebi.ac.uk/pdbsum/5uqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uqh ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uqh OCA], [http://pdbe.org/5uqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uqh RCSB], [http://www.ebi.ac.uk/pdbsum/5uqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uqh ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Campylobacter jejuni jejuni]] | |||
[[Category: IMP dehydrogenase]] | [[Category: IMP dehydrogenase]] | ||
[[Category: Anderson, W F]] | [[Category: Anderson, W F]] |
Revision as of 22:44, 15 November 2017
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p182Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p182
Structural highlights
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