5y6p: Difference between revisions
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''' | {{Large structure}} | ||
==Structure of the phycobilisome from the red alga Griffithsia pacifica== | |||
<StructureSection load='5y6p' size='340' side='right' caption='[[5y6p]], [[Resolution|resolution]] 3.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5y6p]] is a 862 chain structure with sequence from [http://en.wikipedia.org/wiki/Griffithsia_pacifica Griffithsia pacifica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y6P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y6P FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYC:PHYCOCYANOBILIN'>CYC</scene>, <scene name='pdbligand=PEB:PHYCOERYTHROBILIN'>PEB</scene>, <scene name='pdbligand=PUB:PHYCOUROBILIN'>PUB</scene>, <scene name='pdbligand=PVN:PHYCOVIOLOBILIN'>PVN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y6p OCA], [http://pdbe.org/5y6p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y6p RCSB], [http://www.ebi.ac.uk/pdbsum/5y6p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y6p ProSAT]</span></td></tr> | |||
</table> | |||
{{Large structure}} | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Life on Earth depends on photosynthesis for its conversion of solar energy to chemical energy. Photosynthetic organisms have developed a variety of light-harvesting systems to capture sunlight. The largest light-harvesting complex is the phycobilisome (PBS), the main light-harvesting antenna in cyanobacteria and red algae. It is composed of phycobiliproteins and linker proteins but the assembly mechanisms and energy transfer pathways of the PBS are not well understood. Here we report the structure of a 16.8-megadalton PBS from a red alga at 3.5 A resolution obtained by single-particle cryo-electron microscopy. We modelled 862 protein subunits, including 4 linkers in the core, 16 rod-core linkers and 52 rod linkers, and located a total of 2,048 chromophores. This structure reveals the mechanisms underlying specific interactions between linkers and phycobiliproteins, and the formation of linker skeletons. These results provide a firm structural basis for our understanding of complex assembly and the mechanisms of energy transfer within the PBS. | |||
Structure of phycobilisome from the red alga Griffithsia pacifica.,Zhang J, Ma J, Liu D, Qin S, Sun S, Zhao J, Sui SF Nature. 2017 Nov 2;551(7678):57-63. doi: 10.1038/nature24278. Epub 2017 Oct 18. PMID:29045394<ref>PMID:29045394</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 5y6p" style="background-color:#fffaf0;"></div> | |||
[[Category: | == References == | ||
[[Category: Liu, D | <references/> | ||
[[Category: Ma, J | __TOC__ | ||
</StructureSection> | |||
[[Category: Griffithsia pacifica]] | |||
[[Category: Liu, D S]] | |||
[[Category: Ma, J F]] | |||
[[Category: Sui, S F]] | |||
[[Category: Sun, S]] | [[Category: Sun, S]] | ||
[[Category: Zhang, J]] | [[Category: Zhang, J]] | ||
[[Category: Photosynthesis]] | |||
[[Category: Phycobilisome]] | |||
Revision as of 10:44, 15 November 2017
Structure of the phycobilisome from the red alga Griffithsia pacificaStructure of the phycobilisome from the red alga Griffithsia pacifica
Structural highlights
Warning: this is a large structure, and loading might take a long time or not happen at all. Publication Abstract from PubMedLife on Earth depends on photosynthesis for its conversion of solar energy to chemical energy. Photosynthetic organisms have developed a variety of light-harvesting systems to capture sunlight. The largest light-harvesting complex is the phycobilisome (PBS), the main light-harvesting antenna in cyanobacteria and red algae. It is composed of phycobiliproteins and linker proteins but the assembly mechanisms and energy transfer pathways of the PBS are not well understood. Here we report the structure of a 16.8-megadalton PBS from a red alga at 3.5 A resolution obtained by single-particle cryo-electron microscopy. We modelled 862 protein subunits, including 4 linkers in the core, 16 rod-core linkers and 52 rod linkers, and located a total of 2,048 chromophores. This structure reveals the mechanisms underlying specific interactions between linkers and phycobiliproteins, and the formation of linker skeletons. These results provide a firm structural basis for our understanding of complex assembly and the mechanisms of energy transfer within the PBS. Structure of phycobilisome from the red alga Griffithsia pacifica.,Zhang J, Ma J, Liu D, Qin S, Sun S, Zhao J, Sui SF Nature. 2017 Nov 2;551(7678):57-63. doi: 10.1038/nature24278. Epub 2017 Oct 18. PMID:29045394[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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