3lxx: Difference between revisions
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==Crystal structure of human GTPase IMAP family member 4== | ==Crystal structure of human GTPase IMAP family member 4== | ||
<StructureSection load='3lxx' size='340' side='right' caption='[[3lxx]], [[Resolution|resolution]] 2.15Å' scene=''> | <StructureSection load='3lxx' size='340' side='right' caption='[[3lxx]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lxw|3lxw]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lxw|3lxw]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GIMAP4, IAN1, IMAP4, MSTP062 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GIMAP4, IAN1, IMAP4, MSTP062 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lxx OCA], [http://pdbe.org/3lxx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lxx RCSB], [http://www.ebi.ac.uk/pdbsum/3lxx PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lxx OCA], [http://pdbe.org/3lxx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lxx RCSB], [http://www.ebi.ac.uk/pdbsum/3lxx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lxx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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[[Category: Tong, Y]] | [[Category: Tong, Y]] | ||
[[Category: Weigelt, J]] | [[Category: Weigelt, J]] | ||
[[Category: Coiled coil]] | |||
[[Category: Gtp-binding]] | [[Category: Gtp-binding]] | ||
[[Category: Immune system]] | [[Category: Immune system]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
Revision as of 11:01, 8 November 2017
Crystal structure of human GTPase IMAP family member 4Crystal structure of human GTPase IMAP family member 4
Structural highlights
Function[GIMA4_HUMAN] May play a role in regulating lymphocyte apoptosis (By similarity). Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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