5td9: Difference between revisions

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'''Unreleased structure'''


The entry 5td9 is ON HOLD  until Paper Publication
==Structure of Human Enolase 2==
 
<StructureSection load='5td9' size='340' side='right' caption='[[5td9]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
Authors: Leonard, P.G., Muller, F.L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5td9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TD9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TD9 FirstGlance]. <br>
Description: Structure of Human Enolase 2
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ENO2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
[[Category: Muller, F.L]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
[[Category: Leonard, P.G]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5td9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5td9 OCA], [http://pdbe.org/5td9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5td9 RCSB], [http://www.ebi.ac.uk/pdbsum/5td9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5td9 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/ENOG_HUMAN ENOG_HUMAN]] Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Phosphopyruvate hydratase]]
[[Category: Leonard, P G]]
[[Category: Muller, F L]]
[[Category: Carbohydrate metabolism]]
[[Category: Enolase gamma]]
[[Category: Glycolysis]]
[[Category: Lyase]]
[[Category: Neuron specific enolase]]

Revision as of 14:46, 6 November 2017

Structure of Human Enolase 2Structure of Human Enolase 2

Structural highlights

5td9 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:ENO2 (HUMAN)
Activity:Phosphopyruvate hydratase, with EC number 4.2.1.11
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[ENOG_HUMAN] Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).

5td9, resolution 2.32Å

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