1zrt: Difference between revisions

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Revision as of 01:40, 31 March 2008

File:1zrt.gif

, resolution 3.50Å

Ligands:

, , ,

Activity:

Ubiquinol--cytochrome-c reductase, with EC number 1.10.2.2

Related:

1PP9, 1KB9

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

Rhodobacter capsulatus cytochrome bc1 complex with stigmatellin bound

OverviewOverview

Ubihydroquinone: cytochrome (cyt)c oxidoreductase, or cyt bc (1), is a widespread, membrane integral enzyme that plays a crucial role during photosynthesis and respiration. It is one of the major contributors of the electrochemical proton gradient, which is subsequently used for ATP synthesis. The simplest form of the cyt bc (1) is found in bacteria, and it contains only the three ubiquitously conserved catalytic subunits: the Fe-S protein, cyt b and cyt c (1). Here we present a preliminary X-ray structure of Rhodobacter capsulatus cyt bc (1) at 3.8 A and compare it to the available structures of its homologues from mitochondria and chloroplast. Using the bacterial enzyme structure, we highlight the structural similarities and differences that are found among the three catalytic subunits between the members of this family of enzymes. In addition, we discuss the locations of currently known critical mutations, and their implications in terms of the cyt bc (1) catalysis.

About this StructureAbout this Structure

1ZRT is a Protein complex structure of sequences from Rhodobacter capsulatus. Full crystallographic information is available from OCA.

ReferenceReference

X-Ray Structure of Rhodobacter Capsulatus Cytochrome bc (1): Comparison with its Mitochondrial and Chloroplast Counterparts., Berry EA, Huang LS, Saechao LK, Pon NG, Valkova-Valchanova M, Daldal F, Photosynth Res. 2004;81(3):251-75. PMID:16034531

Page seeded by OCA on Mon Mar 31 01:40:47 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 4: / Line 4: @@
 |PDB= 1zrt |SIZE=350|CAPTION= <scene name='initialview01'>1zrt</scene>, resolution 3.50&Aring;
 |SITE=
-|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SMA:STIGMATELLIN+A'>SMA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene> and <scene name='pdbligand=FES:FE2/S2 (INORGANIC) CLUSTER'>FES</scene>
+|LIGAND= <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SMA:STIGMATELLIN+A'>SMA</scene>
-|ACTIVITY= [http://en.wikipedia.org/wiki/Ubiquinol--cytochrome-c_reductase Ubiquinol--cytochrome-c reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.2.2 1.10.2.2]
+|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquinol--cytochrome-c_reductase Ubiquinol--cytochrome-c reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.2.2 1.10.2.2] </span>
 |GENE=
+|DOMAIN=
+|RELATEDENTRY=[[1pp9|1PP9]], [[1kb9|1KB9]]
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zrt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zrt OCA], [http://www.ebi.ac.uk/pdbsum/1zrt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1zrt RCSB]</span>
 }}
@@ Line 29: / Line 32: @@
 [[Category: Saechao, L K.]]
 [[Category: Valkova-Valchanov, M.]]
-[[Category: FES]]
-[[Category: HEC]]
-[[Category: HEM]]
-[[Category: SMA]]
 [[Category: complex iii]]
 [[Category: cytochrome b]]
@@ Line 45: / Line 44: @@
 [[Category: stigmatellin]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:39:06 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:40:47 2008''