3fxv: Difference between revisions
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==Identification of an N-oxide pyridine GW4064 analogue as a potent FXR agonist== | ==Identification of an N-oxide pyridine GW4064 analogue as a potent FXR agonist== | ||
<StructureSection load='3fxv' size='340' side='right' caption='[[3fxv]], [[Resolution|resolution]] 2.26Å' scene=''> | <StructureSection load='3fxv' size='340' side='right' caption='[[3fxv]], [[Resolution|resolution]] 2.26Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=643:6-(4-{[3-(3,5-DICHLOROPYRIDIN-4-YL)-5-(1-METHYLETHYL)ISOXAZOL-4-YL]METHOXY}-2-METHYLPHENYL)-1-METHYL-1H-INDOLE-3-CARBOXYLIC+ACID'>643</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=643:6-(4-{[3-(3,5-DICHLOROPYRIDIN-4-YL)-5-(1-METHYLETHYL)ISOXAZOL-4-YL]METHOXY}-2-METHYLPHENYL)-1-METHYL-1H-INDOLE-3-CARBOXYLIC+ACID'>643</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR1H4, hCG_20893 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR1H4, hCG_20893 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fxv OCA], [http://pdbe.org/3fxv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fxv RCSB], [http://www.ebi.ac.uk/pdbsum/3fxv PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fxv OCA], [http://pdbe.org/3fxv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fxv RCSB], [http://www.ebi.ac.uk/pdbsum/3fxv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fxv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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</div> | </div> | ||
<div class="pdbe-citations 3fxv" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3fxv" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Activator]] | [[Category: Activator]] | ||
[[Category: Acyltransferase]] | [[Category: Acyltransferase]] | ||
[[Category: Alternative splicing]] | |||
[[Category: Bile acid]] | [[Category: Bile acid]] | ||
[[Category: Cholesterol]] | [[Category: Cholesterol]] | ||
[[Category: Chromosomal rearrangement]] | |||
[[Category: Dna-binding]] | [[Category: Dna-binding]] | ||
[[Category: Hormone receptor]] | [[Category: Hormone receptor]] | ||
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[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Polymorphism]] | |||
[[Category: Proto-oncogene]] | [[Category: Proto-oncogene]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
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[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Ubl conjugation]] | |||
[[Category: Zinc]] | |||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||