YbgF: Difference between revisions

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[[Image:YbgF.jpg|200px|left|thumb| The Structure of YbgF<ref name='Gerding'>PMID: 17233825</ref>  ]]
[[Image:YbgF.jpg|200px|left|thumb| The Structure of YbgF<ref name='Gerding'>PMID: 17233825</ref>  ]]


 
__TOC__
==Structure==
==Structure==
'''YbgF''' is a periplasmic protein with an N-terminal coiled coil domain (NTD) and a C-terminal tetratricopeptide domain (TPR), both of which are autonomous<ref name='Gerding'>PMID: 17233825</ref>.  As seen in the <scene name='42/429024/Cv/1'>3D structure 2WZ7</scene>, the NTD forms an elongated trimer which is connected via a flexible linker to the TPR trimer, <scene name='42/429024/Cv/2'>as seen in 2XEV</scene>.  This connection can be cleaved by proteases<ref name='Krachler'>PMID: 20816983</ref>.
'''YbgF''' is a periplasmic protein with an N-terminal coiled coil domain (NTD) and a C-terminal tetratricopeptide domain (TPR), both of which are autonomous<ref name='Gerding'>PMID: 17233825</ref>.  As seen in the <scene name='42/429024/Cv/1'>3D structure 2WZ7</scene>, the NTD forms an elongated trimer which is connected via a flexible linker to the TPR trimer, <scene name='42/429024/Cv/2'>as seen in 2XEV</scene>.  This connection can be cleaved by proteases<ref name='Krachler'>PMID: 20816983</ref>.

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Laura McCauley, Michal Harel, Alexander Berchansky, Joel L. Sussman