3dxg: Difference between revisions

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==Ribonuclease A- uridine 5' phosphate complex==
==Ribonuclease A- uridine 5' phosphate complex==
<StructureSection load='3dxg' size='340' side='right' caption='[[3dxg]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
<StructureSection load='3dxg' size='340' side='right' caption='[[3dxg]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dxh|3dxh]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dxh|3dxh]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dxg OCA], [http://pdbe.org/3dxg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dxg RCSB], [http://www.ebi.ac.uk/pdbsum/3dxg PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dxg OCA], [http://pdbe.org/3dxg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dxg RCSB], [http://www.ebi.ac.uk/pdbsum/3dxg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dxg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 11:58, 25 October 2017

Ribonuclease A- uridine 5' phosphate complexRibonuclease A- uridine 5' phosphate complex

Structural highlights

3dxg is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Pancreatic ribonuclease, with EC number 3.1.27.5
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. delCardayre SB, Ribo M, Yokel EM, Quirk DJ, Rutter WJ, Raines RT. Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11. Protein Eng. 1995 Mar;8(3):261-73. PMID:7479688

3dxg, resolution 1.39Å

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OCA