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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dax ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dax ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Nadp]] | [[Category: Nadp]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Polymorphism]] | |||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Steroid metabolism]] | [[Category: Steroid metabolism]] |
Revision as of 11:45, 25 October 2017
Crystal structure of human CYP7A1Crystal structure of human CYP7A1
Structural highlights
Function[CP7A1_HUMAN] Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Cholesterol 7-alpha-monooxygenase
- Human
- Arrowsmith, C H
- Bochkarev, A
- Bountra, C
- Dombrovski, L
- Dong, A
- Edwards, A M
- Loppnau, P
- Park, H
- Structural genomic
- Strushkevich, N V
- Tempel, W
- Wilkstrom, M
- Cholesterol
- Cholesterol 7-alpha hydroxylase
- Cholesterol metabolism
- Cytochrome p450
- Endoplasmic reticulum
- Heme
- Iron
- Lipid metabolism
- Membrane
- Metal-binding
- Microsome
- Monooxygenase
- Nadp
- Oxidoreductase
- Polymorphism
- Sgc
- Steroid metabolism