Lysin

Function Lysin (Lys) is a protein which cleaves cell walls. Egg Lysin, a protein from abalone sperm, creates a hole in the envelope of the egg, permitting the sperm to pass through the envelope and fuse with the egg. Structural highlights The structure of lysin, refined at 1.9 angstroms resolution, reveals an alpha-helical, amphipathic molecule. . you can see the alpha helixes in pink. exhibits three features: two tracks of basic residues that span the length of the molecule, a solvent-exposed cluster of ,(in green) and an extended amino-terminal hypervariable domain that is species-specific. The structure suggests possible mechanisms of action. 3D structure of lysin Updated on 29-May-2025 1lis, 1lyn, 2lis, 2lyn, 3lyn, 5ii7, 5ii8, 5ii9 – aLys - abalone 5iia, 5iib, 5mr3 – aLys + vitelline envelope sperm lysin receptor 1nkl – NK-Lys – pig – NMR 4cvd – Lys – bacteriophage CP-7 1h09 – bLys – bacteriophage CP-1 1oba – bLys + choline 2ixu – bLys + peptidoglycan analog 2ixv, 2j8f, 2j8g – bLys (mutant) + peptidoglycan analog 2mk5 – GH15Lys residues 368-495 – phage GH15 – NMR 4olk – GH15Lys CHAP domain residues 1-165 4ols – GH15Lys amidase domain residues 165-403

spinqualitylabelsall models Abalone lysin (PDB code 1lis) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image