Human growth hormone: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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 HGH is phosphorylated on Ser residues 132 and 176 (Giorgianni, Beranova-Giorgianni, and Desiderio, 2004)<ref>PMID:14997482</ref>. Other research has indicated possible phosphorylation of Tyr residues 35 and 42.  However, these phosphorylations were only investigated in carcinoma cells with constitutively active epidermal growth factor-stimulated tyrosine kinase (Baldwin et al., 1983)<ref>PMID:6600511</ref>.  The overall influence of these post-translational modifications on hGH activity has yet to be determined.
-'''Metal Binding Sites'''<br/>
-Histidine 18  /* May be best just to add scene link featuring these. The coordinates listed in the previous version don't really say much. */
-Histidine 21  /* May be best just to add scene link featuring these. The coordinates listed in the previous version don't really say much. */
-Glutamine 174  /* May be best just to add scene link featuring these. The coordinates listed in the previous version don't really say much. */
 ==Receptor Binding Site==