2pk8: Difference between revisions

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==Crystal structure of an uncharacterized protein PF0899 from Pyrococcus furiosus==
==Crystal structure of an uncharacterized protein PF0899 from Pyrococcus furiosus==
<StructureSection load='2pk8' size='340' side='right' caption='[[2pk8]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='2pk8' size='340' side='right' caption='[[2pk8]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AUC:GOLD+(I)+CYANIDE+ION'>AUC</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AUC:GOLD+(I)+CYANIDE+ION'>AUC</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF0899 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF0899 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pk8 OCA], [http://pdbe.org/2pk8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pk8 RCSB], [http://www.ebi.ac.uk/pdbsum/2pk8 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pk8 OCA], [http://pdbe.org/2pk8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pk8 RCSB], [http://www.ebi.ac.uk/pdbsum/2pk8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pk8 ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==

Revision as of 12:27, 18 October 2017

Crystal structure of an uncharacterized protein PF0899 from Pyrococcus furiosusCrystal structure of an uncharacterized protein PF0899 from Pyrococcus furiosus

Structural highlights

2pk8 is a 1 chain structure with sequence from Pyrfu. This structure supersedes the now removed PDB entry 1she. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:PF0899 (PYRFU)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The hypothetical protein PF0899 is a 95-residue peptide from the hyperthermophilic archaeon Pyrococcus furiosus that represents a gene family with six members. P. furiosus ORF PF0899 has been cloned, expressed and crystallized and its structure has been determined by the Southeast Collaboratory for Structural Genomics (http://www.secsg.org). The structure was solved using the SCA2Structure pipeline from multiple data sets and has been refined to 1.85 A against the highest resolution data set collected (a presumed gold derivative), with a crystallographic R factor of 21.0% and R(free) of 24.0%. The refined structure shows some structural similarity to a wedge-shaped domain observed in the structure of the major capsid protein from bacteriophage HK97, suggesting that PF0899 may be a structural protein.

Structure of the hypothetical protein PF0899 from Pyrococcus furiosus at 1.85 A resolution.,Kelley LL, Dillard BD, Tempel W, Chen L, Shaw N, Lee D, Newton MG, Sugar FJ, Jenney FE Jr, Lee HS, Shah C, Poole FL 3rd, Adams MW, Richardson JS, Richardson DC, Liu ZJ, Wang BC, Rose J Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jul 1;63(Pt, 7):549-52. Epub 2007 Jun 11. PMID:17620707[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

  1. Kelley LL, Dillard BD, Tempel W, Chen L, Shaw N, Lee D, Newton MG, Sugar FJ, Jenney FE Jr, Lee HS, Shah C, Poole FL 3rd, Adams MW, Richardson JS, Richardson DC, Liu ZJ, Wang BC, Rose J. Structure of the hypothetical protein PF0899 from Pyrococcus furiosus at 1.85 A resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jul 1;63(Pt, 7):549-52. Epub 2007 Jun 11. PMID:17620707 doi:10.1107/S1744309107024049

2pk8, resolution 1.85Å

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