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==Structure of Hen Egg-White Lysozyme Determined from crystals grown in pH 7.5==
==Structure of Hen Egg-White Lysozyme Determined from crystals grown in pH 7.5==
<StructureSection load='2hub' size='340' side='right' caption='[[2hub]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
<StructureSection load='2hub' size='340' side='right' caption='[[2hub]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2htx|2htx]], [[2hu1|2hu1]], [[2hu3|2hu3]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2htx|2htx]], [[2hu1|2hu1]], [[2hu3|2hu3]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hub OCA], [http://pdbe.org/2hub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hub RCSB], [http://www.ebi.ac.uk/pdbsum/2hub PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hub OCA], [http://pdbe.org/2hub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hub RCSB], [http://www.ebi.ac.uk/pdbsum/2hub PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2hub ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 11:16, 18 October 2017

Structure of Hen Egg-White Lysozyme Determined from crystals grown in pH 7.5Structure of Hen Egg-White Lysozyme Determined from crystals grown in pH 7.5

Structural highlights

2hub is a 1 chain structure with sequence from Chick. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , , ,
Activity:Lysozyme, with EC number 3.2.1.17
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021

2hub, resolution 1.20Å

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