2gw2: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of the peptidyl-prolyl isomerase domain of human cyclophilin G== | ==Crystal structure of the peptidyl-prolyl isomerase domain of human cyclophilin G== | ||
<StructureSection load='2gw2' size='340' side='right' caption='[[2gw2]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='2gw2' size='340' side='right' caption='[[2gw2]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
| Line 6: | Line 7: | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPIG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPIG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gw2 OCA], [http://pdbe.org/2gw2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gw2 RCSB], [http://www.ebi.ac.uk/pdbsum/2gw2 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gw2 OCA], [http://pdbe.org/2gw2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gw2 RCSB], [http://www.ebi.ac.uk/pdbsum/2gw2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gw2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| Line 20: | Line 21: | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gw2 ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gw2 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 11:01, 18 October 2017
Crystal structure of the peptidyl-prolyl isomerase domain of human cyclophilin GCrystal structure of the peptidyl-prolyl isomerase domain of human cyclophilin G
Structural highlights
Function[PPIG_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
| ||||||||||||||||||||
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Human
- Peptidylprolyl isomerase
- Arrowsmith, C H
- Bernstein, G
- Bochkarev, A
- Davis, T
- Dhe-Paganon, S
- Edwards, A M
- Finerty, P J
- Mackenzie, F
- Newman, E M
- Structural genomic
- Sundstrom, M
- Tempel, W
- Weigelt, J
- Cis-trans isomerization
- Isomerase
- Mutant
- Mutation
- Peptidyl-prolyl isomerase
- Ppiase
- Protein folding
- Sgc
- Surface mutagenesis