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==Crystal Structure of Thermoplasma acidophilum 0175 (APC014)==
==Crystal Structure of Thermoplasma acidophilum 0175 (APC014)==
<StructureSection load='1kyt' size='340' side='right' caption='[[1kyt]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='1kyt' size='340' side='right' caption='[[1kyt]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TA0175 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2303 "Thermoplasma acidophila" (sic) Darland et al. 1970])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TA0175 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2303 "Thermoplasma acidophila" (sic) Darland et al. 1970])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kyt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kyt OCA], [http://pdbe.org/1kyt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kyt RCSB], [http://www.ebi.ac.uk/pdbsum/1kyt PDBsum], [http://www.topsan.org/Proteins/MCSG/1kyt TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kyt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kyt OCA], [http://pdbe.org/1kyt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kyt RCSB], [http://www.ebi.ac.uk/pdbsum/1kyt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kyt ProSAT], [http://www.topsan.org/Proteins/MCSG/1kyt TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 11:10, 12 October 2017

Crystal Structure of Thermoplasma acidophilum 0175 (APC014)Crystal Structure of Thermoplasma acidophilum 0175 (APC014)

Structural highlights

1kyt is a 2 chain structure with sequence from "thermoplasma_acidophila"_(sic)_darland_et_al._1970 "thermoplasma acidophila" (sic) darland et al. 1970. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
NonStd Res:
Gene:TA0175 ("Thermoplasma acidophila" (sic) Darland et al. 1970)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[PGP_THEAC] Catalyzes the dephosphorylation of 2-phosphoglycolate. Also has significant, but less efficient, pyrophosphatase activity, since it is able to catalyze the release of phosphate from inorganic pyrophosphate (PPi).[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Kim Y, Yakunin AF, Kuznetsova E, Xu X, Pennycooke M, Gu J, Cheung F, Proudfoot M, Arrowsmith CH, Joachimiak A, Edwards AM, Christendat D. Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum. J Biol Chem. 2004 Jan 2;279(1):517-26. Epub 2003 Oct 10. PMID:14555659 doi:10.1074/jbc.M306054200

1kyt, resolution 1.70Å

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