1yd9: Difference between revisions
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|PDB= 1yd9 |SIZE=350|CAPTION= <scene name='initialview01'>1yd9</scene>, resolution 1.6Å | |PDB= 1yd9 |SIZE=350|CAPTION= <scene name='initialview01'>1yd9</scene>, resolution 1.6Å | ||
|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand=AU:GOLD ION'>AU</scene> | |LIGAND= <scene name='pdbligand=AU:GOLD+ION'>AU</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= H2afy ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus]) | |GENE= H2afy ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus]) | ||
|DOMAIN= | |||
|RELATEDENTRY=[[1hjz|1HJZ]] | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yd9 OCA], [http://www.ebi.ac.uk/pdbsum/1yd9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1yd9 RCSB]</span> | |||
}} | }} | ||
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[[Category: Perche, P Y.]] | [[Category: Perche, P Y.]] | ||
[[Category: Swamy, G Y.S K.]] | [[Category: Swamy, G Y.S K.]] | ||
[[Category: a1pp domain]] | [[Category: a1pp domain]] | ||
[[Category: alpha-beta structure]] | [[Category: alpha-beta structure]] | ||
[[Category: macro-domain]] | [[Category: macro-domain]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:03:40 2008'' | ||
Revision as of 01:03, 31 March 2008
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| , resolution 1.6Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | H2afy (Rattus norvegicus) | ||||||
| Related: | 1HJZ
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
1.6A Crystal Structure of the Non-Histone Domain of the Histone Variant MacroH2A1.1.
OverviewOverview
macroH2A is an H2A variant with a highly unusual structural organization. It has a C-terminal domain connected to the N-terminal histone domain by a linker. Crystallographic and biochemical studies show that changes in the L1 loop in the histone fold region of macroH2A impact the structure and potentially the function of nucleosomes. The 1.6-A X-ray structure of the nonhistone region reveals an alpha/beta fold which has previously been found in a functionally diverse group of proteins. This region associates with histone deacetylases and affects the acetylation status of nucleosomes containing macroH2A. Thus, the unusual domain structure of macroH2A integrates independent functions that are instrumental in establishing a structurally and functionally unique chromatin domain.
About this StructureAbout this Structure
1YD9 is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
ReferenceReference
Structural characterization of the histone variant macroH2A., Chakravarthy S, Gundimella SK, Caron C, Perche PY, Pehrson JR, Khochbin S, Luger K, Mol Cell Biol. 2005 Sep;25(17):7616-24. PMID:16107708
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