5t94: Difference between revisions

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-'''Unreleased structure'''
-The entry 5t94 is ON HOLD  until Paper Publication
+==Crystal structure of Kap60 bound to yeast RCC1 (Prp20)==
+<StructureSection load='5t94' size='340' side='right' caption='[[5t94]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
-Authors: Sankhala, R.S., Lokareddy, R.K., Pumroy, R.A., Cingolani, G.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5t94]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T94 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T94 FirstGlance]. <br>
-Description: Crystal structure of Kap60 bound to yeast RCC1 (Prp20)
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pvz|4pvz]]</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t94 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t94 OCA], [http://pdbe.org/5t94 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t94 RCSB], [http://www.ebi.ac.uk/pdbsum/5t94 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t94 ProSAT]</span></td></tr>
-[[Category: Pumroy, R.A]]
+</table>
-[[Category: Lokareddy, R.K]]
+== Function ==
-[[Category: Sankhala, R.S]]
+[[http://www.uniprot.org/uniprot/RCC1_YEAST RCC1_YEAST]] Guanine nucleotide exchange factor that promotes the exchange of GSP1/GSP2-bound GDP by GTP and controls RNA metabolism and transport. Involved in yeast pheromone response pathway and in mRNA metabolism. Involved in nuclear pore complex (NPC) assembly and required for mRNA and ribosome nuclear export. Binds chromatin and is involved NPC-mediated transcriptional control.<ref>PMID:2548085</ref> <ref>PMID:2277633</ref> <ref>PMID:1666302</ref> <ref>PMID:1865879</ref> <ref>PMID:1398069</ref> <ref>PMID:7679070</ref> <ref>PMID:8070652</ref> <ref>PMID:9971735</ref> <ref>PMID:11071906</ref> <ref>PMID:11142374</ref> <ref>PMID:11509570</ref> <ref>PMID:11589573</ref> <ref>PMID:12654904</ref> <ref>PMID:16365162</ref>  [[http://www.uniprot.org/uniprot/IMA1_YEAST IMA1_YEAST]] Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs (By similarity).<ref>PMID:7565597</ref> <ref>PMID:10913188</ref> <ref>PMID:21075847</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Cingolani, G]]
+[[Category: Lokareddy, R K]]
+[[Category: Pumroy, R A]]
+[[Category: Sankhala, R S]]
+[[Category: Importin alpha]]
+[[Category: Nl]]
+[[Category: Nuclear import]]
+[[Category: Protein transport - nuclear protein complex]]
+[[Category: Rcc1 like domain]]
+[[Category: Rld]]