5i4e: Difference between revisions

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'''Unreleased structure'''


The entry 5i4e is ON HOLD  until Paper Publication
==Crystal Structure of Human Nonmuscle Myosin 2C motor domain==
 
<StructureSection load='5i4e' size='340' side='right' caption='[[5i4e]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
Authors: Chinthalapudi, K., Heissler, S.M., Preller, M., Sellers, J.R., Manstein, D.J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5i4e]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5I4E FirstGlance]. <br>
Description: Crystal Structure of Human Nonmuscle Myosin 2C motor domain
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AOV:ADP+ORTHOVANADATE'>AOV</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5i4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i4e OCA], [http://pdbe.org/5i4e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i4e RCSB], [http://www.ebi.ac.uk/pdbsum/5i4e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5i4e ProSAT]</span></td></tr>
[[Category: Sellers, J.R]]
</table>
[[Category: Heissler, S.M]]
== Disease ==
[[http://www.uniprot.org/uniprot/MYH14_HUMAN MYH14_HUMAN]] Peripheral neuropathy-myopathy-hoarseness-hearing loss syndrome;Autosomal dominant non-syndromic sensorineural deafness type DFNA. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[[http://www.uniprot.org/uniprot/MYH14_HUMAN MYH14_HUMAN]] Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.  
__TOC__
</StructureSection>
[[Category: Chinthalapudi, K]]
[[Category: Chinthalapudi, K]]
[[Category: Manstein, D.J]]
[[Category: Heissler, S M]]
[[Category: Manstein, D J]]
[[Category: Preller, M]]
[[Category: Preller, M]]
[[Category: Sellers, J R]]
[[Category: Motor protein]]

Revision as of 08:17, 6 October 2017

Crystal Structure of Human Nonmuscle Myosin 2C motor domainCrystal Structure of Human Nonmuscle Myosin 2C motor domain

Structural highlights

5i4e is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

[MYH14_HUMAN] Peripheral neuropathy-myopathy-hoarseness-hearing loss syndrome;Autosomal dominant non-syndromic sensorineural deafness type DFNA. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.

Function

[MYH14_HUMAN] Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.

5i4e, resolution 2.25Å

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OCA