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| ==Crystal structure of the motor domain of human kinesin family member C1==
| | #REDIRECT [[5wdh]] This PDB entry is obsolete and replaced by 5wdh |
| <StructureSection load='2rep' size='340' side='right' caption='[[2rep]], [[Resolution|resolution]] 2.60Å' scene=''>
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| == Structural highlights ==
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| <table><tr><td colspan='2'>[[2rep]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2REP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2REP FirstGlance]. <br>
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| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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| <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIFC1, HSET, KNSL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rep OCA], [http://pdbe.org/2rep PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rep RCSB], [http://www.ebi.ac.uk/pdbsum/2rep PDBsum]</span></td></tr>
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| </table>
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| == Function ==
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| [[http://www.uniprot.org/uniprot/KIFC1_HUMAN KIFC1_HUMAN]] Minus end-directed microtubule-dependent motor required for bipolar spindle formation. May contribute to movement of early endocytic vesicles.<ref>PMID:15843429</ref>
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| == Evolutionary Conservation ==
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| [[Image:Consurf_key_small.gif|200px|right]]
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| Check<jmol>
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| <jmolCheckbox>
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| <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/re/2rep_consurf.spt"</scriptWhenChecked>
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| <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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| <text>to colour the structure by Evolutionary Conservation</text>
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| </jmolCheckbox>
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| </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rep ConSurf].
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| <div style="clear:both"></div>
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| ==See Also==
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| *[[Kinesin|Kinesin]]
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| == References ==
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| <references/>
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| __TOC__
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| </StructureSection>
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| [[Category: Human]]
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| [[Category: Arrowsmith, C H]]
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| [[Category: Bochkarev, A]]
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| [[Category: Brothers, G]]
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| [[Category: Edwards, A M]]
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| [[Category: He, H]]
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| [[Category: Landry, R]]
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| [[Category: Park, H]]
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| [[Category: Structural genomic]]
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| [[Category: Shen, Y]]
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| [[Category: Sundstrom, M]]
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| [[Category: Tempel, W]]
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| [[Category: Wang, J]]
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| [[Category: Weigelt, J]]
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| [[Category: Zhu, H]]
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| [[Category: Adp]]
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| [[Category: Atp-binding]]
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| [[Category: Cell cycle]]
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| [[Category: Cell division]]
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| [[Category: Endosome]]
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| [[Category: Kinesin]]
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| [[Category: Microtubule]]
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| [[Category: Mitosis]]
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| [[Category: Motor domain]]
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| [[Category: Motor protein]]
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| [[Category: Nucleotide-binding]]
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| [[Category: Nucleus]]
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| [[Category: Phosphorylation]]
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| [[Category: Sgc]]
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This PDB entry is obsolete and replaced by 5wdh