1xo8: Difference between revisions

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Revision as of 00:52, 31 March 2008

File:1xo8.jpg

Domains:

LEA_2

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

Solution structure of AT1g01470 from Arabidopsis Thaliana

OverviewOverview

We report the three-dimensional structure of a late embryogenesis abundant (LEA) protein from Arabidopsis thaliana gene At1g01470.1. This protein is a member of Pfam cluster PF03168, and has been classified as a LEA14 protein. LEA proteins are expressed under conditions of cellular stress, such as desiccation, cold, osmotic stress, and heat. The structure, which was determined by NMR spectroscopy, revealed that the At1g01470.1 protein has an alphabeta-fold consisting of one alpha-helix and seven beta-strands that form two antiparallel beta-sheets. The closest structural homologs were discovered to be fibronectin Type III domains, which have <7% sequence identity. Because fibronectins from animal cells have been shown to be involved in cell adhesion, cell motility, wound healing, and maintenance of cell shape, it is interesting to note that in plants wounding or stress results in the overexpression of a protein with fibronectin Type III structural features.

About this StructureAbout this Structure

1XO8 is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

ReferenceReference

Solution structure of a late embryogenesis abundant protein (LEA14) from Arabidopsis thaliana, a cellular stress-related protein., Singh S, Cornilescu CC, Tyler RC, Cornilescu G, Tonelli M, Lee MS, Markley JL, Protein Sci. 2005 Oct;14(10):2601-9. Epub 2005 Sep 9. PMID:16155204

Page seeded by OCA on Mon Mar 31 00:52:23 2008

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OCA

@@ Line 8: / Line 8: @@
 |GENE=
 |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam03168 LEA_2]</span>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xo8 OCA], [http://www.ebi.ac.uk/pdbsum/1xo8 PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1xo8 RCSB]</span>
+|RELATEDENTRY=
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xo8 OCA], [http://www.ebi.ac.uk/pdbsum/1xo8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xo8 RCSB]</span>
 }}
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 [[Category: unknown function]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:12:19 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:52:23 2008''