1xl5: Difference between revisions
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|PDB= 1xl5 |SIZE=350|CAPTION= <scene name='initialview01'>1xl5</scene>, resolution 1.73Å | |PDB= 1xl5 |SIZE=350|CAPTION= <scene name='initialview01'>1xl5</scene>, resolution 1.73Å | ||
|SITE= | |SITE= | ||
|LIGAND= | |LIGAND= <scene name='pdbligand=190:N-{(1S)-1-(3-BROMOBENZYL)-4-[(4-BROMOPHENYL)SULFONYL]-6-METHYL-2-OXOHEPTYL}-2-(2,6-DIMETHYLPHENOXY)ACETAMIDE'>190</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> | ||
|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span> | ||
|GENE= gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1]) | |GENE= gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1]) | ||
|DOMAIN= | |||
|RELATEDENTRY=[[1hvi|1HVI]], [[1ajx|1AJX]] | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xl5 OCA], [http://www.ebi.ac.uk/pdbsum/1xl5 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xl5 RCSB]</span> | |||
}} | }} | ||
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[[Category: Klebe, G.]] | [[Category: Klebe, G.]] | ||
[[Category: Specker, E.]] | [[Category: Specker, E.]] | ||
[[Category: amidhydroxysulfone inhibitor]] | [[Category: amidhydroxysulfone inhibitor]] | ||
[[Category: aspartyl protease]] | [[Category: aspartyl protease]] | ||
[[Category: hiv protease]] | [[Category: hiv protease]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:51:09 2008'' | ||
Revision as of 00:51, 31 March 2008
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| , resolution 1.73Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | gag-pol (Human immunodeficiency virus 1) | ||||||
| Activity: | HIV-1 retropepsin, with EC number 3.4.23.16 | ||||||
| Related: | 1HVI, 1AJX
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
HIV-1 Protease in complex with amidhyroxysulfone
About this StructureAbout this Structure
1XL5 is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
ReferenceReference
An old target revisited: two new privileged skeletons and an unexpected binding mode for HIV-protease inhibitors., Specker E, Bottcher J, Lilie H, Heine A, Schoop A, Muller G, Griebenow N, Klebe G, Angew Chem Int Ed Engl. 2005 May 13;44(20):3140-4. PMID:15822136
Page seeded by OCA on Mon Mar 31 00:51:09 2008