P73: Difference between revisions
Jump to navigation
Jump to search
Michal Harel (talk | contribs) No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='3mx2' size='400' side='right' caption='Dimeric human p73 DNA-binding domain complex with Tris, glycerol and Zn+2 ion (grey), [[2xwc]]' scene='' pspeed='8'> | |||
'''p73''' is a protein related to p53 tumor suppressor. It is involved in cell cycle regulation and induction of apoptosis<ref>PMID:9891077</ref>. p73 has several variants differing in their C- or N-terminal. p73 contains DNA-binding domain (DBD residues 112-312); tetramerization domain (TD residues 351-398). | '''p73''' is a protein related to p53 tumor suppressor. It is involved in cell cycle regulation and induction of apoptosis<ref>PMID:9891077</ref>. p73 has several variants differing in their C- or N-terminal. p73 contains DNA-binding domain (DBD residues 112-312); tetramerization domain (TD residues 351-398). | ||
== Structural highlights == | |||
</StructureSection> | |||
== 3D Structures of p73 == | == 3D Structures of p73 == | ||
Revision as of 14:50, 24 August 2017
p73 is a protein related to p53 tumor suppressor. It is involved in cell cycle regulation and induction of apoptosis[1]. p73 has several variants differing in their C- or N-terminal. p73 contains DNA-binding domain (DBD residues 112-312); tetramerization domain (TD residues 351-398). Structural highlights |
| ||||||||||
3D Structures of p733D Structures of p73
Updated on 24-August-2017
1cok – hp73 C terminal – human – NMR
2kby – hp73 TD – NMR
2xwc – hp73 DBD (mutant)
3vd0, 3vd1, 3vd2, 4g82, 4g83, 4guo, 4guq – hp73 DBD + DNA
4a63 – hp73 DBD + apoptosis stimulating of p53 protein