2v0z: Difference between revisions
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== | |||
==Crystal Structure of Renin with Inhibitor 10 (Aliskiren)== | |||
<StructureSection load='2v0z' size='340' side='right' caption='[[2v0z]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2v0z' size='340' side='right' caption='[[2v0z]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2v0z]] is a 2 chain structure | <table><tr><td colspan='2'>[[2v0z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V0Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V0Z FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C41:ALISKIREN'>C41</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C41:ALISKIREN'>C41</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bbs|1bbs]], [[1bil|1bil]], [[1bim|1bim]], [[1hrn|1hrn]], [[1pr7|1pr7]], [[1pr8|1pr8]], [[1rne|1rne]], [[1uhq|1uhq]], [[2bks|2bks]], [[2bkt|2bkt]], [[2g20|2g20]], [[2ren|2ren]], [[2v10|2v10]], [[2v11|2v11]], [[2v12|2v12]], [[2v13|2v13]], [[2v16|2v16]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bbs|1bbs]], [[1bil|1bil]], [[1bim|1bim]], [[1hrn|1hrn]], [[1pr7|1pr7]], [[1pr8|1pr8]], [[1rne|1rne]], [[1uhq|1uhq]], [[2bks|2bks]], [[2bkt|2bkt]], [[2g20|2g20]], [[2ren|2ren]], [[2v10|2v10]], [[2v11|2v11]], [[2v12|2v12]], [[2v13|2v13]], [[2v16|2v16]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v0z OCA], [http://pdbe.org/2v0z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v0z RCSB], [http://www.ebi.ac.uk/pdbsum/2v0z PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v0z OCA], [http://pdbe.org/2v0z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v0z RCSB], [http://www.ebi.ac.uk/pdbsum/2v0z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v0z ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Renin]] | [[Category: Renin]] | ||
[[Category: Cohen, N C]] | [[Category: Cohen, N C]] | ||
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[[Category: Stutz, S]] | [[Category: Stutz, S]] | ||
[[Category: Wood, J M]] | [[Category: Wood, J M]] | ||
[[Category: Alternative splicing]] | |||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Inhibitor-complex]] | [[Category: Inhibitor-complex]] | ||
[[Category: Polymorphism]] | |||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||