Tumor necrosis factor receptor: Difference between revisions
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<StructureSection load='1ext' size='450' side='right' caption='Structure of human TNFR extracellular domain complex with sulfate and Mg+2 ion (green) (PDB code [[1ext]]).' scene='59/590824/Cv/4'> | <StructureSection load='1ext' size='450' side='right' caption='Structure of human TNFR extracellular domain complex with sulfate and Mg+2 ion (green) (PDB code [[1ext]]).' scene='59/590824/Cv/4' pspeed='8'> | ||
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== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains (CRD). The <scene name='59/590824/Cv/5'>CRD domains are ca. 40 amino-acid long and contain 4-6 cysteine residues</scene>. The CRDs are involved in binding of TNF<ref>PMID:8939750</ref>. <scene name='59/590824/Cv/ | The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains (CRD). The <scene name='59/590824/Cv/5'>CRD domains are ca. 40 amino-acid long and contain 4-6 cysteine residues</scene>. The CRDs are involved in binding of TNF<ref>PMID:8939750</ref>. <scene name='59/590824/Cv/7'>Mg coordination site</scene>. Water molecules shown as red spheres. | ||
</StructureSection> | </StructureSection> | ||