Interleukin-1 receptor-associated kinase: Difference between revisions
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*IRAK4 | *IRAK4 | ||
**[[2nru]], [[2nry]], [[2oib]], [[2o8y]] – hIRAK4 kinase domain - human<br /> | **[[2nru]], [[2nry]], [[2oib]], [[2o8y]], [[4rmz]] – hIRAK4 kinase domain - human<br /> | ||
**[[4u97]], [[4u9a]] - hIRAK4 kinase domain (mutant)<br /> | **[[4u97]], [[4u9a]] - hIRAK4 kinase domain (mutant)<br /> | ||
**[[1wh4]] – mIRAK4 DEATH domain – mouse – NMR<br /> | **[[1wh4]] – mIRAK4 DEATH domain – mouse – NMR<br /> | ||
**[[2a9i]] - mIRAK4 DEATH domain<br /> | **[[2a9i]] - mIRAK4 DEATH domain<br /> | ||
**[[2oic]], [[4xs2]] - hIRAK4 kinase domain + staurosporine<br /> | **[[2oic]], [[4xs2]] - hIRAK4 kinase domain + staurosporine<br /> | ||
**[[4y73]], [[4yo6]], [[4yp8]], [[4ztl]], [[4ztm]], [[4ztn]] - hIRAK4 kinase domain + inhibitor<br /> | **[[4y73]], [[4yo6]], [[4yp8]], [[4ztl]], [[4ztm]], [[4ztn]], [[5kx7]], [[5kx8]], [[5t1s]], [[5t1t]], [[5uiq]], [[5uir]], [[5uis]], [[5uit]], [[5uiu]] - hIRAK4 kinase domain + inhibitor<br /> | ||
**[[2oid]] - hIRAK4 kinase domain + AMPPNP<br /> | **[[2oid]] - hIRAK4 kinase domain + AMPPNP<br /> | ||
**[[3mop]] - hIRAK4 DEATH domain + hIRAK2 DEATH domain + MYD88<br /> | |||
}} | }} | ||
== References == | == References == | ||
Revision as of 11:57, 22 June 2017
FunctionInterleukin-1 receptor-associated kinase (IRAK) is a kinase involved in signaling innate immune responses from Toll-like receptors and interleukin-1 receptor-related proteins[1]. RelevanceIRAK4 is involved in early recognition of pathogens and the initiation of inflammation when fighting infection. DiseaseIRAK4 deficiency is a disorder which causes recurrent bacterial infections. |
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3D structures of IRAK43D structures of IRAK4
Updated on 22-June-2017