Insulin-like growth factor receptor: Difference between revisions

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Revision as of 12:51, 19 June 2017 view source Michal Harel (talk \| contribs) 31,761 edits No edit summary ← Older edit		Revision as of 12:52, 19 June 2017 view source Michal Harel (talk \| contribs) 31,761 edits No edit summary Newer edit →
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	<StructureSection load='3i81' size='450' side='right' scene='' caption='Human insulin-like growth factor 1 receptor (PDB code [[3i81]])'>		<StructureSection load='3i81' size='450' side='right' scene='' caption='Human insulin-like growth factor 1 receptor complex with inhibitor (PDB code [[3i81]])'>
	'''Insulin-like growth factor receptors''' (IGFR) are transmembrane receptors which are stimulated by insulin-like growth factors (IGF). IGFR contains 2 extracellular α chains and 2 transmembranal β chains. Upon binding of IGF, a tyrosine in the β chain becomes autophosphorylated and triggers a cascade of intracellular signaling.		'''Insulin-like growth factor receptors''' (IGFR) are transmembrane receptors which are stimulated by insulin-like growth factors (IGF). IGFR contains 2 extracellular α chains and 2 transmembranal β chains. Upon binding of IGF, a tyrosine in the β chain becomes autophosphorylated and triggers a cascade of intracellular signaling.