Gp41

Function Gp41 is a subunit of the envelope protein of retrovirus. Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120. For more details see Hiv env proteins. Relevance Fusion inhibitory drugs which bind to Gp41 prevent the attachment of the HIV-1 virus to the cell.

spinqualitylabelsall models Core structure of gp41 from the HIV envelope glycoprotein, 1aik. Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of Gp413D Structures of Gp41

Updated on 04-June-2017

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• Gp41 from HIV-1
  • 1aik – Gp41
    
  • 1env, 3k9a – Gp41 (mutant)
    
  • 1szt – Gp41 thermostable domain
    
  • 3cp1, 3cyo – Gp41 thermostable domain (mutant)
    
  • 1df4, 1df5, 1qr8, 1qr9, 1dlb, 1jpx – Gp41 core
    
  • 1f23, 1k33, 1k34, 1i5x, 1i5y, 2ot5 – Gp41 core (mutant)
    
  • 5ka6, 5ka5 – Gp41 transmembrane (mutant)
    
  • 2z2t, 2zzo, 3aha, 3vie, 2r3c, 2r5b, 2r5d, 3l36, 3l37, 3vgy, 3vh7, 3vtp, 3vu5, 3vu6, 5h0n – Gp41 N-heptad repeat + Gp41 fusion inhibitor peptide
    
  • 2zfc – Gp41 N-peptide
    
  • 4i2l – Gp41 N-peptide (mutant)
    
  • 3u91 – Gp41 N-terminal
    
  • 4hlr – Gp41 N-terminal (mutant)
    
  • 5v8l, 5v8m, 5uty, 5utf, 5um8, 5jsa, 5js9, 5i8h, 5d9q, 5cjx, 5c7k – Gp41 + Gp120 + antibody
    
  • 5u1f, 5thr – Gp41 + Gp120 + antibody + CD4
    
  • 5fyk, 5fyj, 4nco – Gp41 + Gp120 (mutant) + antibody
    
  • 5hm1 – Gp41 + llama antibody
    
  • 3o3x – arGp41 - artificial
    
  • 4dzu – arGp41 + 3-α
    
  • 4dzv – arGp41 + 4-α/β
    
• Gp41 from Simian Immunodeficiency Virus
  • 2siv – Gp41 core
    
  • 2ezo, 2ezp, 2ezq, 2ezr, 2ezs, 1qce – Gp41 core - NMR
    
  • 1qbz, 1jq0 – Gp41 core (mutant)