5vsv: Difference between revisions

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New page: ==Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225== <StructureSection load='5vsv' size='340' side='right' caption='[[5...
 
m Protected "5vsv" [edit=sysop:move=sysop]
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Revision as of 16:33, 24 May 2017

Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225

Structural highlights

5vsv is a 4 chain structure. This structure supersedes the now removed PDB entry 5uzo. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:IMP dehydrogenase, with EC number 1.1.1.205
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[A0A127ELD1_CLOPF] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]

5vsv, resolution 2.21Å

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OCA