Rop protein: Difference between revisions
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<StructureSection load='1rop' size='400' side='right' scene='' caption='E. coli Rop protein [[1rop]]'> | |||
==Function== | ==Function== | ||
<scene name='Rop_protein/Wt_rop/1'>Rop</scene> '''(Repressor Of Primer)''' is a small homodimeric RNA-binding protein that is involved in the regulation of copy number of the ColE1 plasmids of E.coli, where it is encoded<ref>pmid 2462471</ref>. Its structure has been studied using both X-ray crystallography<ref>PMID:3681971</ref> and NMR<ref>PMID:1841691</ref>. | <scene name='Rop_protein/Wt_rop/1'>Rop</scene> '''(Repressor Of Primer)''' is a small homodimeric RNA-binding protein that is involved in the regulation of copy number of the ColE1 plasmids of E.coli, where it is encoded<ref>pmid 2462471</ref>. Its structure has been studied using both X-ray crystallography<ref>PMID:3681971</ref> and NMR<ref>PMID:1841691</ref>. | ||
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*re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle([[1yo7]]) | *re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle([[1yo7]]) | ||
*ALA2ILE2-6, repacted the hydrophobic core and a new fold ([[1f4n]]) | *ALA2ILE2-6, repacted the hydrophobic core and a new fold ([[1f4n]]) | ||
</StructureSection> | |||
==3D structures of Rop protein== | ==3D structures of Rop protein== | ||