Ribosome recycling factor: Difference between revisions
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<StructureSection load='1ek8' size='340' side='right' caption='E. coli ribosome recycling factor complex with decyloxy-methanol and Hg+2 ion (PDB code [[1ek8]])' scene='70/706271/Cv/1'> | <StructureSection load='1ek8' size='340' side='right' caption='E. coli ribosome recycling factor complex with decyloxy-methanol and Hg+2 ion (PDB code [[1ek8]])' scene='70/706271/Cv/1' pspeed='8'> | ||
== Function == | == Function == | ||
'''Ribosome recycling factor''' (RRF) acts in releasing the ribosome from mRNA after completion of protein synthesis. | '''Ribosome recycling factor''' (RRF) acts in releasing the ribosome from mRNA after completion of protein synthesis. | ||
RRF splits the ribosome into its small and large subunits. RRF is used together with elongation factor G in achieving this separation<ref>PMID:16043510</ref>. RRF is a structural mimic of tRNA but binds to the ribosome differently than the A-site, P-site or E-site tRNA. | RRF splits the ribosome into its small and large subunits. RRF is used together with elongation factor G in achieving this separation<ref>PMID:16043510</ref>. RRF is a structural mimic of tRNA but binds to the ribosome differently than the A-site, P-site or E-site tRNA. | ||
*<scene name='70/706271/Cv/2'>1st Hg coordination</scene>. | *<scene name='70/706271/Cv/2'>1st Hg coordination site</scene>. | ||
*<scene name='70/706271/Cv/3'>2nd and 3rd Hg coordination sites</scene>. | |||
</StructureSection> | </StructureSection> | ||