5tid: Difference between revisions

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'''Unreleased structure'''


The entry 5tid is ON HOLD  until Paper Publication
==X-ray structure of acyl-CoA thioesterase I, TesA, mutant M141L/Y145K/L146K at pH 5 in complex with octanoic acid==
 
<StructureSection load='5tid' size='340' side='right' caption='[[5tid]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
Authors: Thoden, J.B., Holden, H.M., Grisewood, M.J., Hernandez Lozada, N.J., Gifford, N.P., Mendez-Perez, D., Schoenberger, H.A., Allan, M.F., Pfleger, B.F., Marines, C.D.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5tid]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TID FirstGlance]. <br>
Description: X-ray structure of acyl-CoA thioesterase I, TesA, mutant M141L/Y145K/L146K at pH 5 in complex with octanoic acid
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCA:OCTANOIC+ACID+(CAPRYLIC+ACID)'>OCA</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tic|5tic]], [[5tie|5tie]], [[5tif|5tif]]</td></tr>
[[Category: Allan, M.F]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tid OCA], [http://pdbe.org/5tid PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tid RCSB], [http://www.ebi.ac.uk/pdbsum/5tid PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tid ProSAT]</span></td></tr>
[[Category: Thoden, J.B]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/TESA_ECOLI TESA_ECOLI]] Hydrolyzes only long chain acyl thioesters (C12-C18). Specificity similar to chymotrypsin.
__TOC__
</StructureSection>
[[Category: Allan, M F]]
[[Category: Gifford, N P]]
[[Category: Grisewood, M J]]
[[Category: Holden, H M]]
[[Category: Lozada, N J.Hernandez]]
[[Category: Marines, C D]]
[[Category: Mendez-Perez, D]]
[[Category: Mendez-Perez, D]]
[[Category: Grisewood, M.J]]
[[Category: Pfleger, B F]]
[[Category: Marines, C.D]]
[[Category: Schoenberger, H A]]
[[Category: Gifford, N.P]]
[[Category: Thoden, J B]]
[[Category: Schoenberger, H.A]]
[[Category: Fatty acid]]
[[Category: Holden, H.M]]
[[Category: Hydrolase]]
[[Category: Hernandez Lozada, N.J]]
[[Category: Octanoic acid]]
[[Category: Pfleger, B.F]]
[[Category: Tesa]]
[[Category: Thioesterase]]

Revision as of 17:00, 27 April 2017

X-ray structure of acyl-CoA thioesterase I, TesA, mutant M141L/Y145K/L146K at pH 5 in complex with octanoic acidX-ray structure of acyl-CoA thioesterase I, TesA, mutant M141L/Y145K/L146K at pH 5 in complex with octanoic acid

Structural highlights

5tid is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TESA_ECOLI] Hydrolyzes only long chain acyl thioesters (C12-C18). Specificity similar to chymotrypsin.

5tid, resolution 1.20Å

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