Sandbox Reserved 1063: Difference between revisions
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<StructureSection load='3TGN' size='350' side='right' caption='[http://www.rcsb.org/pdb/explore/explore.do?structureId=3TGN Adhesin Competence Regulator (3TGN)]' scene=''> | <StructureSection load='3TGN' size='350' side='right' caption='[http://www.rcsb.org/pdb/explore/explore.do?structureId=3TGN Adhesin Competence Regulator (3TGN)]' scene=''> | ||
===Introduction=== | ===Introduction=== | ||
Adhesin Competence Regulator (<scene name='69/694230/Adcr_space_fill/1'>AdcR</scene>) is a transcriptional regulator that controls the activation of over seventy genes within the bacteria [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae''Streptococcus pneumoniae''] and is a member of the multiple antibiotic resistance regulator (MarR) protein family <ref name="Sanson">DOI:10.1093/nar/gku1304 </ref>. Members of the [http://www.cell.com/current-biology/abstract/S0960-9822(13)00016-X MarR] protein family conserve a number of features including a general triangular shape, a two fold pseudosymmetric homodimer, and a winged helix-turn-helix pattern [https://en.wikipedia.org/wiki/Helix-turn-helix (wHTH)] which can be seen in Figure 1. AdcR exhibits these conserved features as well, while also exhibiting its own distinct features. | Adhesin Competence Regulator (<scene name='69/694230/Adcr_space_fill/1'>AdcR</scene>) is a transcriptional regulator that controls the activation of over seventy genes within the bacteria [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae''Streptococcus pneumoniae''] and is a member of the multiple antibiotic resistance regulator (MarR) protein family <ref name="Sanson">DOI:10.1093/nar/gku1304 </ref>. Members of the [http://www.cell.com/current-biology/abstract/S0960-9822(13)00016-X MarR] protein family conserve a number of features including a general triangular shape, a two fold pseudosymmetric homodimer, and a winged helix-turn-helix pattern [https://en.wikipedia.org/wiki/Helix-turn-helix (wHTH)] which can be seen in Figure 1. AdcR exhibits these conserved features as well, while also exhibiting its own distinct features. | ||