Sandbox Reserved 1063: Difference between revisions
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=== Binding Site 2 === | === Binding Site 2 === | ||
<scene name='69/694230/Binding_site_2/4'>Binding site 2</scene>consists of a highly distorted tetrahedral geometry around the zinc ion. There are three amino acids involved in the binding of the zinc ion (C30, E41, and E107) as well as a water molecule. If Cys30 in binding site 2 is mutated to an alanine, it will have no effect on the ability of the protein to bind DNA <ref name="guerra" />. Therefore, binding site 2 has no significant role in the ability of AdcR to bind to DNA and AdcR is still able to function with no zinc bound present in binding site 2. | <scene name='69/694230/Binding_site_2/4'>Binding site 2</scene> consists of a highly distorted tetrahedral geometry around the zinc ion. There are three amino acids involved in the binding of the zinc ion (C30, E41, and E107) as well as a water molecule. If Cys30 in binding site 2 is mutated to an alanine, it will have no effect on the ability of the protein to bind DNA <ref name="guerra" />. Therefore, binding site 2 has no significant role in the ability of AdcR to bind to DNA and AdcR is still able to function with no zinc bound present in binding site 2. | ||
=== Hydrogen Bond Network === | === Hydrogen Bond Network === | ||