Circadian clock protein: Difference between revisions
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**[[1r8j]] – SeKaiA <br /> | **[[1r8j]] – SeKaiA <br /> | ||
**[[1suy]], [[1sv1]] – SeKaiA C terminal + KaiC peptide - NMR <br /> | **[[1suy]], [[1sv1]] – SeKaiA C terminal + KaiC peptide - NMR <br /> | ||
**[[5c5e]] – SeKaiA + KaiC peptide <br /> | |||
**[[4g86]] – SeKaiA + DBMIB<br /> | **[[4g86]] – SeKaiA + DBMIB<br /> | ||
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**[[1tf7]], [[2gbl]] – SyKaiC <br /> | **[[1tf7]], [[2gbl]] – SyKaiC <br /> | ||
**[[1u9i]], [[3dvl]], [[3jzm]], [[3k09]], [[3k0a]], [[3k0c]], [[3k0e]], [[3k0f]], [[3s1a]], [[4dug]], [[4ijm]] – SeKaiC (mutant) <br /> | **[[1u9i]], [[3dvl]], [[3jzm]], [[3k09]], [[3k0a]], [[3k0c]], [[3k0e]], [[3k0f]], [[3s1a]], [[4dug]], [[4ijm]], [[4o0m]] – SeKaiC (mutant) <br /> | ||
**[[4tl6]] – SeKaiC N terminal <br /> | |||
**[[4tl8]], [[4tl7]] – SeKaiC N terminal C1 domain<br /> | |||
**[[4tl9]], [[4tla]], [[4tlb]], [[4tlc]], [[4tld]], [[4tle]] – SeKaiC N terminal C1 domain (mutant)<br /> | |||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:55, 3 April 2017
Circadian clock proteins measure out the 24 hour circadian rhythm. In cyanobacteria protein KaiA[1] stimulates KaiC[2] which adds phosphate groups to itself. Then KaiC binds to KaiB[3] which inactivates KaiA and causes the number of phosphate groups on KaiC to drop slowly. KaiB disconnects allowing KaiA to start the cycle again.[4] For details of KaiC see Circadian Clock Protein KaiC. Circadian clock protein KaiA from Synechococcus elongatus is (PDB entry 1r8j). |
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3D Structures of circadian clock protein3D Structures of circadian clock protein
Updated on 03-April-2017
ReferencesReferences
- ↑ Ye S, Vakonakis I, Ioerger TR, LiWang AC, Sacchettini JC. Crystal structure of circadian clock protein KaiA from Synechococcus elongatus. J Biol Chem. 2004 May 7;279(19):20511-8. Epub 2004 Mar 8. PMID:15007067 doi:10.1074/jbc.M400077200
- ↑ Pattanayek R, Wang J, Mori T, Xu Y, Johnson CH, Egli M. Visualizing a circadian clock protein: crystal structure of KaiC and functional insights. Mol Cell. 2004 Aug 13;15(3):375-88. PMID:15304218 doi:10.1016/j.molcel.2004.07.013
- ↑ . PMID:15716247
- ↑ Harmer SL, Panda S, Kay SA. Molecular bases of circadian rhythms. Annu Rev Cell Dev Biol. 2001;17:215-53. PMID:11687489 doi:http://dx.doi.org/10.1146/annurev.cellbio.17.1.215