5jns: Difference between revisions

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'''Unreleased structure'''


The entry 5jns is ON HOLD  until Paper Publication
==Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with phosphate==
 
<StructureSection load='5jns' size='340' side='right' caption='[[5jns]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
Authors: Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5jns]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JNS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JNS FirstGlance]. <br>
Description: Crystal Structure of human Low Molecular Weight Protein Tyrosine Phosphatase type A (LMPTP-A) complexed with phosphate
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jnt|5jnt]], [[5jnr|5jnr]], [[5jnv|5jnv]], [[5jnu|5jnu]], [[5jnw|5jnw]]</td></tr>
[[Category: Liddington, R.C]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jns OCA], [http://pdbe.org/5jns PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jns RCSB], [http://www.ebi.ac.uk/pdbsum/5jns PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jns ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PPAC_HUMAN PPAC_HUMAN]] Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.
__TOC__
</StructureSection>
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Aleshin, A E]]
[[Category: Bankston, L]]
[[Category: Bottini, N]]
[[Category: Cadwell, G]]
[[Category: Cadwell, G]]
[[Category: Aleshin, A.E]]
[[Category: Liddington, R C]]
[[Category: Bankston, L]]
[[Category: Stanford, S M]]
[[Category: Hydrolase]]
[[Category: Lmptp]]
[[Category: Lmw-ptp]]
[[Category: Protein tyrosine phosphatase]]

Revision as of 16:45, 29 March 2017

Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with phosphateCrystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with phosphate

Structural highlights

5jns is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:Protein-tyrosine-phosphatase, with EC number 3.1.3.48
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PPAC_HUMAN] Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity.

5jns, resolution 1.80Å

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OCA
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