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==Structure of haloalkane dehalogenase variant DhaA101== | |||
<StructureSection load='5flk' size='340' side='right' caption='[[5flk]], [[Resolution|resolution]] 0.99Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5flk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FLK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FLK FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5flk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5flk OCA], [http://pdbe.org/5flk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5flk RCSB], [http://www.ebi.ac.uk/pdbsum/5flk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5flk ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH]] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Haloalkane dehalogenase]] | |||
[[Category: Chaloupkova, R]] | |||
[[Category: Damborsky, J]] | [[Category: Damborsky, J]] | ||
[[Category: Waterman, J]] | [[Category: Waterman, J]] | ||
[[Category: | [[Category: Alpha/beta-hydrolase]] | ||
[[Category: Hydrolase]] | |||
Revision as of 16:42, 29 March 2017
Structure of haloalkane dehalogenase variant DhaA101Structure of haloalkane dehalogenase variant DhaA101
Structural highlights
Function[DHAA_RHORH] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane. |
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