5plh: Difference between revisions

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-'''Unreleased structure'''
-The entry 5plh is ON HOLD
+==PanDDA analysis group deposition -- Crystal Structure of JMJD2D after initial refinement with no ligand modelled (structure 138)==
+<StructureSection load='5plh' size='340' side='right' caption='[[5plh]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
-Authors: Krojer, T.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5plh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5PLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5PLH FirstGlance]. <br>
-Description: PanDDA analysis group deposition --Crystal Structure of JMJD2D after initial refinement with no ligand modelled (structure 138)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5plh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5plh OCA], [http://pdbe.org/5plh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5plh RCSB], [http://www.ebi.ac.uk/pdbsum/5plh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5plh ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/KDM4D_HUMAN KDM4D_HUMAN]] Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.<ref>PMID:16603238</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Arrowsmith, C H]]
+[[Category: Bountra, C]]
+[[Category: Bradley, A R]]
+[[Category: Brandao-Neto, J]]
+[[Category: Brennan, P E]]
+[[Category: Burgess-Brown, N]]
+[[Category: Collins, P]]
+[[Category: Cox, O]]
+[[Category: Delft, F von]]
+[[Category: Dias, A]]
+[[Category: Douangamath, A]]
+[[Category: Edwards, A]]
+[[Category: Fairhead, M]]
 [[Category: Krojer, T]]
+[[Category: MacLean, E]]
+[[Category: Ng, J]]
+[[Category: Oppermann, U]]
+[[Category: Pearce, N M]]
+[[Category: Renjie, Z]]
+[[Category: Sethi, R]]
+[[Category: Szykowska, A]]
+[[Category: Talon, R]]
+[[Category: Vollmar, M]]
+[[Category: Wright, N]]
+[[Category: Epigenetic]]
+[[Category: Jmj domain]]
+[[Category: Oxidoreductase]]
+[[Category: Pandda]]
+[[Category: Sgc - diamond i04-1 fragment screening]]