Rho GTPase activating protein: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
<StructureSection load='1ow3' size='450' side='right' caption='Human RhoGAP 1 (grey) complex with RhoA (green), GDP, MgF3 and Mg+2 ions (PDB code [[1ow3]])' scene='75/750307/Cv/1' pspeed='8'>
<StructureSection load='1ow3' size='450' side='right' caption='Human RhoGAP 1 (magenta) complex with RhoA (cyan), GDP, MgF3 and Mg+2 ions (PDB code [[1ow3]])' scene='75/750307/Cv/1' pspeed='8'>
__TOC__
__TOC__
== Function ==
== Function ==
Line 8: Line 8:


== Structural highlights ==
== Structural highlights ==
The active site of RhoGAP contains a catalytic arginine and GDP<ref>PMID:11927263</ref>.
The <scene name='75/750307/Cv/3'>active site of RhoGAP</scene> contains a <scene name='75/750307/Cv/4'>catalytic arginine</scene> and GDP<ref>PMID:11927263</ref>. Water molecules shown as red spheres. <scene name='75/750307/Cv/4'>Mg/MgF3 coordination site</scene>.




Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky