1tf3: Difference between revisions

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|PDB= 1tf3 |SIZE=350|CAPTION= <scene name='initialview01'>1tf3</scene>
|PDB= 1tf3 |SIZE=350|CAPTION= <scene name='initialview01'>1tf3</scene>
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tf3 OCA], [http://www.ebi.ac.uk/pdbsum/1tf3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1tf3 RCSB]</span>
}}
}}


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[[Category: Wright, P E.]]
[[Category: Wright, P E.]]
[[Category: Wuttke, D S.]]
[[Category: Wuttke, D S.]]
[[Category: ZN]]
[[Category: 5s rna gene]]
[[Category: 5s rna gene]]
[[Category: complex (transcription regulation/dna)]]
[[Category: complex (transcription regulation/dna)]]
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[[Category: zinc finger]]
[[Category: zinc finger]]


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Revision as of 23:55, 30 March 2008

File:1tf3.gif


PDB ID 1tf3

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Ligands: , , , ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES


OverviewOverview

The three N-terminal zinc fingers of transcription factor IIIA bind in the DNA major groove. Substantial packing interfaces are formed between adjacent fingers, the linkers lose their intrinsic flexibility upon DNA binding, and several lysine side chains implicated in DNA recognition are dynamically disordered.

About this StructureAbout this Structure

1TF3 is a Single protein structure of sequence from Xenopus laevis. Full crystallographic information is available from OCA.

ReferenceReference

Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA., Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE, Nat Struct Biol. 1997 Aug;4(8):605-8. PMID:9253405

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