1tf3: Difference between revisions
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|PDB= 1tf3 |SIZE=350|CAPTION= <scene name='initialview01'>1tf3</scene> | |PDB= 1tf3 |SIZE=350|CAPTION= <scene name='initialview01'>1tf3</scene> | ||
|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene> | |LIGAND= <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tf3 OCA], [http://www.ebi.ac.uk/pdbsum/1tf3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1tf3 RCSB]</span> | |||
}} | }} | ||
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[[Category: Wright, P E.]] | [[Category: Wright, P E.]] | ||
[[Category: Wuttke, D S.]] | [[Category: Wuttke, D S.]] | ||
[[Category: 5s rna gene]] | [[Category: 5s rna gene]] | ||
[[Category: complex (transcription regulation/dna)]] | [[Category: complex (transcription regulation/dna)]] | ||
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[[Category: zinc finger]] | [[Category: zinc finger]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:55:09 2008'' |
Revision as of 23:55, 30 March 2008
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Ligands: | , , , , | ||||||
Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
Coordinates: | save as pdb, mmCIF, xml |
TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES
OverviewOverview
The three N-terminal zinc fingers of transcription factor IIIA bind in the DNA major groove. Substantial packing interfaces are formed between adjacent fingers, the linkers lose their intrinsic flexibility upon DNA binding, and several lysine side chains implicated in DNA recognition are dynamically disordered.
About this StructureAbout this Structure
1TF3 is a Single protein structure of sequence from Xenopus laevis. Full crystallographic information is available from OCA.
ReferenceReference
Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA., Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE, Nat Struct Biol. 1997 Aug;4(8):605-8. PMID:9253405
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